Hepatolenticular degeneration complicated by impaired vision：A case report and literature review
10.19845/j.cnki.zfysjjbzz.2025.0004
- VernacularTitle:肝豆状核变性并发视力下降1例报告并文献复习
- Author:
Liangliang ZHANG
1
;
Yongsheng HAN
2
Author Information
1. 安徽中医药大学，安徽 合肥 230012;安徽中医药大学神经病学研究所附属医院，安徽 合肥 230061
2. 安徽中医药大学，安徽 合肥 230012;安徽中医药大学神经病学研究所，安徽 合肥 230038;皖南医学院，安徽 芜湖 241002
- Publication Type:Journal Article
- Keywords:
Hepatolenticular degeneration;
Impaired vision;
Optic atrophy;
Optic neuritis
- From:
Journal of Apoplexy and Nervous Diseases
2025;42(1):19-22
- CountryChina
- Language:Chinese
-
Abstract:
Hepatolenticular degeneration （HLD），also known as Wilson disease (WD) is an uncommon hereditary disorder of the nervous system， characterized by hepatic impairment， extrapyramidal manifestations， psychiatric symptoms， and renal dysfunction， while impaired vision is a rare comorbidity. This article conducts a retrospective analysis of visual acuity changes， treatment， and prognosis of a female patient， aged 22 years， who were diagnosed with HLD complicated by bilateral neuritis in an affiliated hospital of Anhui University of Chinese Medicine in 2022， and a literature review was performed. The findings suggest that impaired vision is a rare manifestation of HLD. Ophthalmologists should consider the possibility of HLD in patients with optic atrophy and optic neuritis， and early intravenous administration of methylprednisolone may help to improve prognosis.
