Recommendations for solving the dilemma of end-stage patients participating in clinical trials under the palliative care philosophy
10.12026/j.issn.1001-8565.2025.07.17
- VernacularTitle:安宁疗护理念下破解终末期患者参与临床试验困境的建议
- Author:
Xue HONG
1
;
Lijie XU
2
;
Haiyan LI
1
;
Yahong CHEN
3
Author Information
1. Department of Scientific Research， the Third Hospital of Peking University，Beijing 100191， China
2. School of Nursing， Capital Medical University ，Beijing 100069， China
3. Department of Respiratory Medicine， Peking University Third Hospital， Beijing 100191， China
- Publication Type:Journal Article
- Keywords:
palliative care;
end-stage patients;
clinical trials
- From:
Chinese Medical Ethics
2025;38(7):924-928
- CountryChina
- Language:Chinese
-
Abstract:
Palliative care is recognized as an effective measure to improve the quality of life for patients with end-stage diseases， and the significance and role of such patients participating in clinical trials to conquer major diseases has also become a broad consensus. However， due to the special physical， psychological， and social conditions of terminal trial participants， the ethical problems encountered in the trial process are more serious and complex. Drawing on ethical practice experience， these seemingly common phenomena and issues were deeply analyzed. Combined with the palliative care philosophy for end-stage patients， this paper proposed a series of improvement suggestions throughout the entire life cycle of clinical trials， hoping to promote the quality improvement of clinical research in which end-stage patients participate as subjects， while effectively protecting the safety and rights of the subjects and ensuring they receive appropriate palliative care during their participation in clinical trials or clinical-related scientific research.
