Relationship between intolerance of uncertainty and obsessive-compulsive disorder pathology and neurobiological mechanisms
10.11886/scjsws20240604002
- VernacularTitle:无法忍受不确定性与强迫症精神病理的关系及脑神经机制
- Author:
Bin LI
1
;
Jiaxin JIANG
1
;
Hailong LI
2
;
Zhong ZHENG
3
;
Xiaoqi HUANG
2
Author Information
1. Mental Health Center， West China Hospital， Sichuan University， Sichuan， Chengdu 610041， China
2. Huaxi MR Research Center ， Institution of Radiology and Medical Imaging， West China Hospital， Sichuan University， Chengdu 610041， China
3. Center for Neurological Function Test and Neuromodulation， West China Xiamen Hospital， Sichuan University， Xiamen 361021， China
- Publication Type:Journal Article
- Keywords:
Obsessive-compulsive disorder;
Intolerance of uncertainty;
Magnetic resonance imaging;
Psychopathology;
Neural mechanisms
- From:
Sichuan Mental Health
2025;38(3):193-197
- CountryChina
- Language:Chinese
-
Abstract:
Obsessive-compulsive disorder （OCD） is a highly disabling mental disorder that impairs patients' social function and quality of life， and impose a substantial economic burden. Intolerance of uncertainty （IU） refers to a cognitive bias in perceiving， interpreting and responding to uncertain situations or events. IU is closely associated with the cognitive patterns of OCD patients. Based on magnetic resonance imaging （MRI）， this paper discusses the research progress of the relationship between IU and psychopathological characteristics of OCD， and put forward the research direction， aims to provide evidence-based references for the development of optimized therapeutic interventions for OCD.
