Giant Brunner’s Gland Adenoma Diagnosed by Endoscopic Ultrasound-guided Fine-needle Biopsy
10.52927/jdcr.2025.13.1.82
- Author:
Ji Hoon PARK
1
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Korea
- Publication Type:CASE REPORT
- From:
Journal of Digestive Cancer Research
2025;13(1):82-85
- CountryRepublic of Korea
- Language:English
-
Abstract:
Brunner’s gland adenoma is a rare benign duodenal tumor often discovered incidentally during endoscopy. A 48-year-old male presented with weight loss, dizziness, and melena. Endoscopic examination revealed a large, smooth-surfaced, hyperemic polypoid lesion in the second portion of the duodenum. Computed tomography identified a 6-cm hypoechoic mass, and positron emission tomography demonstrated increased F-fluorodeoxyglucose uptake, raising the suspicion of lymphoma. However, endoscopic ultrasound-guided fine-needle biopsy (EUSFNB) confirmed the diagnosis of a giant Brunner’s gland adenoma. EUS-FNB findings revealed a submucosal mass with clear margins, heterogeneous echogenicity, and cystic components.This case highlights the role of EUS-FNB in distinguishing Brunner’s gland adenoma from other submucosal lesions, thereby avoiding unnecessary invasive procedures. Advanced diagnostic techniques are essential in the management of rare duodenal tumors.
