Massive Perivillous Fibrin Deposition in Placenta.
- Author:
Dae Woon EOM
1
;
Gil Hyun KANG
;
Chung Hyun CHO
;
Sang Wook YI
;
Han Moie PARK
;
Sang Su LEE
;
U Seog SON
Author Information
1. Department of Pathology, University of Ulsan College of Medicine, Gangneung, Korea. edwjyh@gnah.co.kr
- Publication Type:Case Report
- Keywords:
Placenta;
Chorionic villi;
Massive perivillous fibrin deposition (MFD)
- From:Korean Journal of Pathology
2008;42(4):236-239
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Massive perivillous fibrin deposition (MFD) is a rare condition characterized by heavy accumulation of fibrin in intervillous or perivillous spaces encasing villi throughout the placenta. This condition may cause varying degrees of placental insufficiency, leading to a significantly increased risk of intrauterine growth retardation, intrauterine death, and pre-term delivery. However, the objective criteria for the diagnosis of MFD have not been clearly established. We report a case of MFD associated with intrauterine growth retardation and preterm premature rupture of membranes.