Advances in the vortex vein and choroidal vasculature of central serous chorioretinopathy
10.3980/j.issn.1672-5123.2025.7.07
- VernacularTitle:中心性浆液性脉络膜视网膜病变的涡静脉及脉络膜血流的研究进展
- Author:
Yijia FAN
1
;
Yanhui WANG
1
;
Yifan WANG
1
;
Yilei LIANG
1
;
Lifei WANG
1
Author Information
1. Hebei Medical University, Shijiazhuag 050011, Hebei Province, China
- Publication Type:Journal Article
- Keywords:
central serous chorioretinopathy;
vortex vein;
choroid;
pathogenesis
- From:
International Eye Science
2025;25(7):1079-1083
- CountryChina
- Language:Chinese
-
Abstract:
Central serous chorioretinopathy(CSC), the first described pachychoroid disease, is characterized by visual distortions and loss of vision, which are commonly seen in middle-aged male. Research has demonstrated that ocular blood flow in CSC is in a state of overload, characterized by the dilation of vortex vein ampullae and choroidal vasculature. The obstruction of venous outflow is linked to scleral thickness, while the choriocapillaris exhibits perfusion deficits due to compression from the engorged vascular layer. Over time, vascular remodeling occurs, with venous anastomoses forming to create alternative drainage pathways and mitigate blood stasis. These abnormalities in vortex vein dynamics and choroidal circulation play a critical role in elucidating the underlying pathogenesis and clinical manifestations of CSC. This review highlights the alterations in vortex vein and choroidal vasculature in CSC, hoping to understand how the changes of blood flow affect the course of CSC and their correlation with treatment response. By evaluating blood flow dynamics, we aim to determine the disease stage more accurately, optimize therapeutic strategies, and ultimately enhance patient outcomes.
