Recognizing hepatic manifestations in rheumatic diseases
- VernacularTitle:重视风湿免疫病的肝脏表现
- Author:
Chengyao WANG
1
;
Yanying LIU
1
Author Information
- Publication Type:Journal Article
- Keywords: Rheumatic Diseases; Hepatic Insufficiency; Autoimmune Liver Diseases
- From: Journal of Clinical Hepatology 2025;41(5):801-805
- CountryChina
- Language:Chinese
- Abstract: The liver is one of the organs most commonly affected by rheumatic diseases. Hepatic abnormalities in patients with rheumatic diseases can result from a variety of factors， including direct liver involvement by the disease itself， coexistence with primary liver disease， and drug-induced liver injury. When liver indicators are abnormal， a thorough differential diagnosis is required. For unexplained liver dysfunction， routine testing for autoantibodies should be performed to facilitate early identification of underlying autoimmune liver disease. If the etiology remains unclear， a liver biopsy is recommended for a final diagnosis if feasible. Alongside active management of rheumatic diseases， it is necessary to closely monitor liver function， avoid the use of agents that may exacerbate hepatic damage， particularly anti-rheumatic drugs with strong hepatotoxicity， and tailor treatment strategies according to personal specific conditions， so as to minimize liver damage and improve long-term outcome.
