Utilizing a high power light-emitting diode to induce apoptosis of uterine carcinosarcoma (malignant mixed mullerian tumor) cells through a bi-phasic effect
- Author:
Gil Jae JUNG
1
;
Su Jin LEE
;
Yun Dan KANG
;
Seung Hoon WOO
;
Jong Soo KIM
Author Information
- Publication Type:Original article
- From: Medical Lasers 2024;13(3):142-149
- CountryRepublic of Korea
- Language:English
-
Abstract:
Background:Malignant mixed mullerian tumor (MMMT), a carcinoma of the uterus, is a bi-phasic tumor composed of malignant epithelial and mesenchymal components. The treatment of MMMT remains a challenge despite advances in technology. This study is a preliminary investigation of the potential use of high power lightemitting diode (HPLED) modules as an alternative to laser therapy for cancer treatment.
Methods:This study used 656 and 850 nm HPLEDs at 50 mW power output within a non-thermal range duration. The viability and proliferation of the cells were analyzed after irradiation with the HPLEDs.
Results:A significant reduction in cancer cell viability was observed after irradiation with either the 656 or 850 nm HPLED.
Conclusion:This study shows the potential use of HPLEDs for cancer treatment.
