Association between serum creatinine levels at emergency admission and outcomes in patients with exertional heat stroke: a multicenter cohort study
10.5847/wjem.j.1920-8642.2025.051
- Author:
Dingping Jin
1
Author Information
1. Nursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310009, China
- Publication Type:Other Types
- Keywords:
creatinine;
heat stroke
- From:
World Journal of Emergency Medicine
2025;16(3):269-272
- CountryChina
- Language:English
-
Abstract:
Exertional heat stroke (EHS) is a life-threatening condition characterized by profound central nervous system (CNS) dysfunction and core temperature typically >40 °C.[1] This condition involves complex pathophysiological processes in which heat triggers a cascade of dysregulated inflammatory responses, endothelial dysfunction, coagulation abnormalities, and muscle damage. These processes can lead to multiorgan failure, significantly increasing the risk of mortality.[2] Given the severity of EHS, early identification and timely intervention are crucial. However, there are no specific diagnostic markers for EHS,[1] highlighting the need to identify reliable clinical parameters that can assist early decision-making.
