Impact of vestibular dysfunction on cognitive function
10.12025/j.issn.1008-6358.2025.20250094
- VernacularTitle:前庭功能障碍对认知功能的影响
- Author:
Ruiqi ZHANG
1
;
Yanli ZHAO
1
;
Dongmei ZHANG
2
;
Wenyan LI
3
;
Peixia WU
4
Author Information
1. Department of Nursing, Eye & ENT Hospital, Fudan University, Shanghai 200031, China;Fudan University School of Nursing, Shanghai 200032, China.
2. Department of Nursing, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
3. Vertigo and Balance Function Disorders Clinical Center, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
4. Department of Nursing, Eye & ENT Hospital, Fudan University, Shanghai 200031, China;Vertigo and Balance Function Disorders Clinical Center, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
- Publication Type:Monographicreport:Multi-disciplinarydiagnosisandtreatmentofvertigo
- Keywords:
vestibular dysfunction;
cognitive function;
vertigo;
memory
- From:
Chinese Journal of Clinical Medicine
2025;32(2):218-224
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of vestibular dysfunction on various domains of cognitive function, providing a basis for developing comprehensive vestibular-cognitive intervention strategies. Methods A total of 33 patients with confirmed unilateral vestibular dysfunction treated at Eye & ENT Hospital, Fudan University between June 2024 and December 2024. Vestibular function was assessed using vestibular evoked myogenic potential (VEMP), caloric testing, video head impulse test (vHIT), and sensory organization test (SOT). Cognitive function was evaluated using mini-mental state examination (MMSE), Montreal cognitive assessment (MoCA), Stroop color-word test, trail making test (TMT), and auditory verbal learning test (AVLT). Subjective symptoms were assessed using dizziness handicap inventory (DHI). Results In the vestibular function assessment of patients, abnormalities in caloric testing, utricle VEMP and saccule VEMP results were most common, with rates of 87.9%, 57.6%, and 66.7%, respectively; SOT abnormality primarily characterized by impaired vestibular function (21.2%). Spearman correlation analysis showed age, years of education, hearing ability, and emotional state were associated with overall or specific domains of cognitive function in patients. Greater vestibular dysfunction severity was associated with longer TMT-A time (r＝0.443，P＝0.010), most severe damage of short-term (r＝－0.405，P＝0.019) and long-term delayed recalls (r＝－0.537，P＝0.001). Patients with 31-60 of DHI scores showed longer TMT-A time than patients with 0-30 of DHI scores (P＝0.033). Conclusions Patients with vestibular dysfunction exhibit significant impairment in low-frequency semicircular canal and utricle function, which affects attention allocation, information processing speed, and memory performance in cognitive tasks.
