Prevalence and typing of Helicobacter Pylori of 1 866 cases of chronic gastritis in Wuhan
10.3969/j.issn.1006-2483.2025.02.014
- VernacularTitle:武汉地区1866例慢性胃炎幽门螺杆菌检测及分型分析
- Author:
Xun ZHANG
1
;
Feiwen LIAO
2
;
Bo PENG
1
Author Information
1. Department of Gastroenterology , Wuhan Third Hospital , Wuhan , Hubei 430061, China
2. Department of Gastroenterology , Wuhan Sixth Hospital , Wuhan , Hubei 430015, China
- Publication Type:Journal Article
- Keywords:
Chronic gastritis;
Helicobacter pylori;
Detection;
Typing
- From:
Journal of Public Health and Preventive Medicine
2025;36(2):61-64
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate prevalence and immunological properties of Helicobacter pylori (Hp) infection among chronic gastritis population in Wuhan. Methods A total of 1 866 patients with chronic gastritis in Wuhan were selected from May 2021 to December 2023, and Hp antibody and typing in serum were detected by immunoblotting to analyse the infection rate and typing of patients of different genders and age groups, as well as the correlation between Hp infection and the severity of chronic gastritis. Western blotting technique was utilized to detect the Hp antibodies and typing. The infection rates and subtypes were recorded in patients of different genders and ages. Then the correlation between Hp infection and the severity of chronic gastritis were discussed. Results The overall detection rate of Hp infection was 65.38% (1 220/1 866) in 1866 patients, and the prevalence rate of type I infection was higher than that of type II infection [61.31% (748/1 220) vs 38.69% (472/1 220), P<0.05]. No statistical difference was reported in overall infection rate in terms of gender (P>0.05). In terms of gender, the rate of type I infection was higher than that of type II infection [70.08% (431/615) vs 29.92% (184/615), P<0.05], whereas the prevalence of the two types of infections demonstrated no statistical difference in female patients (P>0.05). In terms of age, the prevalence of Hp infection in patients increased with age (2=64.687, P=0.000). The infection rate of type I was higher than type II in the age groups of below 18, 31-40, 41-50 and 51-60 years old (P<0.05), and infection rates of type I and type II yielded no statistical difference in the age groups of 18-30 and ≥60 years old (P>0.05). With the aggravation of chronic gastritis, the infection rate and percentage of type I infections increased, and the percentage of type I infections was higher than that of type II infections (P<0.05). Conclusion Patients with chronic gastritis in Wuhan suffer a high prevalence rate of Hp infection, and the rate of Hp infection increases with the age of the patients, is positively correlated with the severity of the disease, and presents certain typological features.
