Two new glycosides from the Citri Sarcodactylis Fructus
10.16438/j.0513-4870.2024-0753
- VernacularTitle:佛手中的两个新糖苷类化合物
- Author:
Jing-jing MIAO
1
;
Ge-ge XIA
1
;
Ge-ge ZHAO
1
;
Yu-zhong ZHENG
2
;
Yan-zhi WANG
1
Author Information
1. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou
2. School of Food Engineering and Biotechnology, Hanshan Normal University, Guangdong Provincial Key Laboratory of Functional Substances in Medicinal Edible Resources and Healthcare Products, Chaozhou
- Publication Type:Research Article
- Keywords:
italic>Citri Sarcodactylis Fructus;
chemical composition;
separation and dentification;
glycoside
- From:
Acta Pharmaceutica Sinica
2025;60(1):196-200
- CountryChina
- Language:Chinese
-
Abstract:
Six compounds were isolated from the ethyl acetate fraction of Citri Sarcodactylis Fructus by using various column chromatographic methods, such as MCI Gel CHP-20, ODS, Sephadex LH-20, silica gel and semipreparative HPLC. Their structures were identified to be citrusin G (1), citrusin H (2), citrusin E (3), syringin (4), coniferin (5), methylconiferin (6) by NMR, HR-ESI-MS, UV, IR spectra. Compounds 1 and 2 were new secondary metabolism products and 3-6 were obtained from the titled material for the first time. Compound 1 showed anti-renal fibrosis activity in TGF-β1-induced kidney proximal tubular cells.
