A new glycoside from Alstonia mairei Lévl.
10.16438/j.0513-4870.2024-0737
- VernacularTitle:羊角棉中1个新的糖苷类化合物
- Author:
Li-ke WANG
1
;
Bing-yan LI
1
;
Zhen-zhu ZHAO
2
;
Yan-zhi WANG
2
;
Xiao-kun LI
2
;
Wei-sheng FENG
2
;
Ying-ying SI
2
Author Information
1. School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou
2. School of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou; Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou
- Publication Type:Research Article
- Keywords:
italic>Alstonia;
italic>Alstonia mairei Lévl.;
chemical composition;
glycoside;
separation and structural characterization
- From:
Acta Pharmaceutica Sinica
2025;60(1):191-195
- CountryChina
- Language:Chinese
-
Abstract:
Nine compounds were isolated and purified from 90% ethanol extract of Alstonia mairei Lévl by using various chromatographic methods, including silica gel, SephadexLH-20, MCI Gel and ODS column chromatography, combined with semi-preparative liquid phase separation methods. Modern spectroscopic methods (1D and 2D NMR, UV, IR, MS, etc.) were used to identify the structures of the isolated compounds. They were identified as mairoside A (1), 3′,6-di-O-sinaloylsucrose (2), myristic acid (3), methyl myristate (4), ethyl myristate (5), 3,4,5-trimethoxycinnamic acid (6), 3,4,5-trimethoxybenzoic acid (7), vinoline (8), kaempferol-3-O-rutinoside (9), among which compound 1 is a new glycoside, compounds 4 and 5 are new natural products, and the nuclear magnetic data of compound 4 were reported for the first time.
