Risk factors analysis of mutliple drug-resistant organism infection in patients with ventilator-associated pneumonia after operation of cerebral hemorrhage
10.3969/j.issn.1673-9701.2024.27.012
- VernacularTitle:脑出血术后合并VAP患者肺多重耐药菌感染的危险因素分析
- Author:
Shilin CHEN
1
;
Min ZHOU
Author Information
1. 安徽医科大学附属省立医院呼吸科,安徽合肥 230031
- Keywords:
Cerebral hemorrhage;
Ventilator-associated pneumonia;
Multiple drug-resistant organism;
After operation;
Risk factors
- From:
China Modern Doctor
2024;62(27):52-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors and etiological characteristics of pulmonary multiple drug-resistant organism(MDRO)infection and ventilator-associated pneumonia(VAP)in patients with after operation of cerebral hemorrhage.Methods A retrospective analysis was conducted on 103 patients with VAP after operation of cerebral hemorrhage admitted to the Department of Neurointensive Care Unit,Provincial Hospital of Anhui Medical University from January 2020 to January 2022.The clinical baseline data of the patients,including age,gender,total length of stay,underlying diseases,pre-operative Glasgow coma score(GCS),surgery type,surgery time,etc,were collected.The patients were divided into MDRO infection group(n=42)and non MDRO infection group(n=61)according to the pathogenic bacteria for MDRO.Related risk factors of MDRO infection was analyzed by using binary Logistic regression.Results Logistic regression analysis showed that total length of stay and secondary surgery were independent risk factors for MDRO infection(P＜0.05).Among the 103 patients with sputum culture specimens,103 strains of pathogenic bacteria were detected and counted,including 42 MDRO(40.78％),including 17 strains of Acinetobacter baumannii(40.48％),11 strains of Staphylococcus aureus(26.20％),5 strains of Pseudomonas aeruginosa(11.90％),4 strains of Burkholderia cepacia(9.52％),3 strains of Klebsiella pneumoniae(7.14％),1 strain of Streptococcus pneumoniae(2.38％),and 1 strain of Enterobacter cloacae complex(2.38％).Conclusion The longer the total length of stay in patients with VAP after operation of cerebral hemorrhage,the higher the risk of MDRO infection is significantly.The risk of MDRO in patients with secondary surgery is significantly higher than that in patients without secondary surgery.Acinetobacter baumannii etc are common MDRO.
