Full-cycle management of research participant recruitment based on ethical review chain combing and exploration
10.3760/cma.j.cn113565-20240228-00054
- VernacularTitle:基于伦理审查链条式梳理和探索研究参与者招募的全周期管理
- Author:
Weijia ZHOU
1
;
Jiyin ZHOU
Author Information
1. 四川省肿瘤医院 电子科技大学附属肿瘤医院伦理委员会办公室，成都 610041
- Keywords:
Life sciences and medical research involving human beings;
Research participant recruitment;
Ethical review;
Full-cycle management
- From:
Chinese Journal of Medical Science Research Management
2024;37(4):246-252
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aimed to sort out the problems of research participant recruitment based on the chain of ethical review, exploring coping strategies, and managing the whole cycle.Methods:Through policy interpretation and literature review, we analyzed and discussed issues related to recruitment principles, recruitment pathways, recruitment programs, and recruitment advertisements, so as to provide references for the principal investigator to make appropriate plans before recruitment, implement them with high quality during recruitment, and summarize and improve them after recruitment, so as to facilitate the completion of the study with high quality.Results:There were various problems at various stages of recruitment, such as insufficient attention to representativeness before recruitment, lack of a recruitment plan, irrational design and release of recruitment advertisements, lack of attention to fairness and voluntariness during recruitment, failure to face up to possible risks and benefits, coercion or misunderstanding, inappropriate use of specialized medical terminology, insufficient informed consent, lack of attention to the protection of privacy and personal information, failure to summarize and improve the recruitment in a timely manner, lack of attention to the training of recruitment teams and talent development, and lack of regulation of third-party recruitment companies and unregulated behaviors. summarize and improve, insufficient attention to recruitment team training and talent development, and lack of regulation of third-party recruitment companies and irregularities.Conclusions:In order to improve the quality and efficiency of research participant recruitment, proper planning should be made before recruitment to avoid under-representation, select appropriate recruitment methods, formulate a scientific recruitment plan, design standardized and reasonable recruitment advertisements, appropriately increase the frequency of publication of recruitment advertisements, and clarify whether to commission a third-party recruitment company. Recruitment should be carried out with high quality, strictly implement fair and voluntary recruitment, face the potential risks and benefits, avoid coercion or misunderstanding, use easy-to-understand layman's medical terminology, give full informed consent, pay attention to the protection of privacy and personal information, identify and avoid " professional research participants", and pay attention to the recruitment of pregnant women, children, and patients with critical illnesses, etc.. After recruitment, the recruitment should be summarized and perfected, and the recruitment team training and human resources training should be strengthened. After recruitment, we should summarize and improve the recruitment tools, develop and promote systematic recruitment tools, strengthen the training of the recruitment team and talent cultivation, improve the conversion rate of Internet recruitment, give appropriate compensation to the research participants or their guardians, focus on the supervision of irregularities, and set up a system for qualification and supervision of third-party recruitment companies.
