Progress in the detection methods and clinical applications of ceramides
10.3760/cma.j.cn114452-20240109-00015
- VernacularTitle:神经酰胺的检测方法及临床应用进展
- Author:
Benbo LI
1
;
Xiaoliang CHENG
;
Rong WANG
;
Shengkai YAN
Author Information
1. 遵义医科大学附属医院医学检验科，遵义 563003
- Keywords:
Ceramide;
Cardiovascular disease;
Liquid chromatography;
Tandem mass spectrometry;
Clinical laboratory technology
- From:
Chinese Journal of Laboratory Medicine
2024;47(7):827-832
- CountryChina
- Language:Chinese
-
Abstract:
Ceramide plays an important role in sphingolipid metabolic processes. It affects cell signaling pathways, regulates cell and body metabolism, and is related to the occurrence and development of a variety of diseases. In recent years, with the application and development of mass spectrometry technology in the detection of ceramides, ceramides or different combinations of ceramides are found to be potential valuable new biomarkers for clinical diagnosis, risk assessment and prognosis of a variety of diseases. This article reviews the biochemical characteristics, detection methods and clinical application of ceramide, and outlines its application value as biomarkers.
