Updates on spread through air spaces in lung cancer
10.3760/cma.j.cn112434-20240427-00114
- VernacularTitle:肺癌气腔播散的研究新进展
- Author:
Teng XIA
1
;
Shigui XING
Author Information
1. 南京市高淳人民医院胸外科，南京 211300
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2024;40(7):416-422
- CountryChina
- Language:Chinese
-
Abstract:
Spread through air spaces(STAS) represents a relatively novel concept in the pathology of lung cancer, specifically referring to the dissemination of tumor cells into the parenchymal air spaces adjacent to the primary tumor. Recognized by the World Health Organization(WHO) in 2015, STAS has been classified as a new invasive form of lung adenocarcinoma(ADC). Many studies have investigated the role of STAS, revealing its association not merely with the prognosis of ADC but also its influence on the outcomes of other malignant pulmonary neoplasms. Additionally, the underlying mechanisms and predictive models of STAS have received considerable attention in recent years. This paper provides a comprehensive overview of the research advancements and prospects of STAS, examining it from multiple perspectives.
