Recent advance in pathological mechanisms of necroptosis in Parkinson's disease
10.3760/cma.j.cn115354-20240614-00350
- VernacularTitle:坏死性凋亡在帕金森病病理机制中的研究进展
- Author:
Kanghui LIU
1
;
Shuyan ZHANG
Author Information
1. 哈尔滨医科大学附属第四医院神经内科，哈尔滨 150001
- Keywords:
Parkinson's disease;
Necroptosis;
Pathologic mechanism
- From:
Chinese Journal of Neuromedicine
2024;23(7):729-734
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, a large number of studies have found that necroptosis involves in various pathological mechanisms of Parkinson's disease (PD), and can have a beneficial effect on PD by inhibiting the key molecules of necroptosis pathway. This review focuses on the correlations between necrotic apoptosis and various pathologic mechanisms of PD and the latest research progress of inhibitors in PD, aiming to provide theoretical basis for PD treatment and drug target screening.
