Recent advances and reflection on precision medicine in gastric cancer
10.3760/cma.j.cn113855-20240804-00503
- VernacularTitle:胃癌精准治疗的进展和思考
- Author:
Lin CHEN
1
;
Kecheng ZHANG
Author Information
1. 北京大学国际医院胃肠外科，北京 102206
- Keywords:
Stomach neoplasms;
Immunotherapy;
laparoscopy;
Artificial intelligence
- From:
Chinese Journal of General Surgery
2024;39(10):737-741
- CountryChina
- Language:Chinese
-
Abstract:
In China, gastric cancer has a large population base, most patients are diagnosed on late-stage and with poor prognosis, 5-year overall survival rate is only 35.1% The emergence of new technologies, drugs, and equipment provides new opportunities to improve the prognosis of gastric cancer . Omics technologies have expanded our understanding of molecular subtypes in gastric cancer, supporting biomarker-guided precision treatment. For MSI-H patients, perioperative immunotherapy offers potential non-surgical management options. Minimally invasive techniques have shown long-term prognosis results comparable to open surgery, with laparoscopic technology becoming a routine surgical approach for stage Ⅰ-Ⅲ gastric cancer patients. Lymph node dissection should consider tumor location, size, and depth of invasion. Interdisciplinary integration helps to further promote precision treatment of gastric cancer.
