Regulatory roles of transcription factors and receptors in the pathogenesis of acne
- VernacularTitle:转录因子和受体调控痤疮发病机制的研究进展
- Author:
Mengdi FENG
1
;
Wenqing WANG
Author Information
- Keywords: Acne vulgaris; Transcription factors; Receptor of transcription factors; Pathogenesis; Signaling transduction pathway
- From: Chinese Journal of Dermatology 2024;57(6):575-578
- CountryChina
- Language:Chinese
- Abstract: The pathogenesis of acne is still unclear. At present, studies have confirmed roles of transcription factors and receptors in the occurrence and development of acne. Toll-like receptors, insulin-like growth factors, androgen receptors are risk factors for acne, while vitamin D receptors, retinoic acid receptors, epidermal growth factors, peroxisome proliferator-activator receptors are protective factors for acne, all of which are expected to be targets for prevention and treatment of acne. This review focuses on recent research progress in acne-related transcription factors and their receptors, in order to provide new directions for targeted therapy of acne.
