Clinical effects of Xiao'er Chiqiao Qingre Granules combined with conventional treatment on patients with pediatric acute viral infection of lower respiratory tract
10.3969/j.issn.1001-1528.2024.11.015
- VernacularTitle:小儿豉翘清热颗粒联合常规治疗对小儿急性病毒性下呼吸道感染患者的临床疗效
- Author:
Ying-Nan SUN
1
;
Li YANG
;
Bei-Bei CAI
;
Wei PAN
Author Information
1. 上海健康医学院附属嘉定区中心医院,上海 201800
- Keywords:
Xiao'er Chiqiao Qingre Granules;
conventional treatment;
pediatric acute viral infection of lower respiratory tract
- From:
Chinese Traditional Patent Medicine
2024;46(11):3640-3644
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the clinical effects of Xiao'er Chiqiao Qingre Granules combined with conventional treatment on patients with pediatric acute viral infection of lower respiratory tract.METHODS Ninety-nine patients were randomly assigned into control group(49 cases)for intervention of conventional treatment,and observation group(50 cases)for intervention of both Xiao'er Chiqiao Qingre Granules and conventional treatment.The changes in clinical effects,TCM syndrome scores,symptom disappearing time[fever reduction time,nasal congestion(lung rales,wheezing,cough)disappearance time],CRP,TNF-α,CD4+,CD8+,CD4+/CD8+and lung function indices(FEV1,FVC,PEF,MVV)were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05),along with shorter symptom disappearing time(P＜0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,CRP,TNF-α,CD8+(P＜0.05),and increased CD4+,CD4+/CD8+,lung function indices(P＜0.05),especially for the observation group(P＜0.05).CONCLUSION For the patients with pediatric acute viral infection of lower respiratory tract,Xiao'er Chiqiao Qingre Granules combined with conventional treatment can regulate body immunity,decrease CRP,TNF-α levels,reduce inflammatory injury
