Clinical effects of Modified Buzhong Yiqi Decoction combined with Dihuang Decoction on patients with chronic obstructive pulmonary disease in relief period due to Lung-Kidney Qi Deficiency
10.3969/j.issn.1001-1528.2024.07.018
- VernacularTitle:补中益气汤联合地黄汤加减对肺肾气虚型慢性阻塞性肺疾病缓解期患者的临床疗效
- Author:
Ming-Wu ZHANG
1
;
Ming-Na TAN
Author Information
1. 重庆市开州区中医院,重庆 405400
- Keywords:
Buzhong Yiqi Decoction;
Dihuang Decoction;
conventional treatment;
chronic obstructive pulmonary disease;
relief period;
Lung-Kidney Qi Deficiency
- From:
Chinese Traditional Patent Medicine
2024;46(7):2235-2239
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Modified Buzhong Yiqi Decoction combined with Dihuang Decoction on patients with chronic obstructive pulmonary disease in relief period due to Lung-Kidney Qi Deficiency.METHODS One hundred and sixteen patients were randomly assigned into control group(58 cases)for 8-week intervention of conventional treatment,and observation group(58 cases)for 8-week intervention of Modified Buzhong Yiqi Decoction,Dihuang Decoction and conventional treatment.The changes in clinical effects,IL-6,CX3CL1,MMP-9,MCP-1,a1-AT,nutritional indices(ALB,HGB,PALB),pulmonary function indices(FEV1,FEV1/FVC),blood gas indices(PaO2,PaCO2),TCM symptom score and CAT score were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed decreased IL-6,CX3CL1,MMP-9,MCP-1,a1-AT,PaCO2,TCM symptom score,CAT score(P＜0.05),and increased nutritional indices,PaO2,pulmonary function indices(P＜0.05),especially for the observation group(P＜0.05).CONCLUSION For the patients with chronic obstructive pulmonary disease in relief period due to Lung-Kidney Qi Deficiency,Modified Buzhong Yiqi Decoction combined with Dihuang Decoction can alleviate inflammatory responses,improve blood gas indices,correct nutritional disorders,and promote lung function improvement.
