Clinical effects of Shenqi Taohua Siwu Decoction plus Fusui Decoction combined with acupuncture on patients with post-ischemic stroke spastic paralysis due to Qi Deficiency and Blood Stasis
10.3969/j.issn.1001-1528.2024.06.015
- VernacularTitle:参芪桃花四物汤合复遂汤联合针刺对气虚血瘀证缺血性脑梗死恢复期痉挛性瘫痪患者的临床疗效
- Author:
Kun WANG
1
;
Jing REN
;
Wen-Qi YU
;
Da-Wei XU
;
Hui SUN
Author Information
1. 青岛大学附属青岛市海慈医院(青岛市中医医院)针推科,山东青岛 266000
- Keywords:
Shenqi Taohua Siwu Decoction;
Fusui Decoction;
acupuncture;
conventional treatment;
spastic paralysis;
post-ischemic stroke;
recovery stage;
Qi Deficiency and Blood Stasis
- From:
Chinese Traditional Patent Medicine
2024;46(6):1867-1872
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Shenqi Taohua Siwu Decoction plus Fusui Decoction combined with acupuncture on patients with post-ischemic stroke spastic paralysis due to Qi Deficiency and Blood Stasis.METHODS Ninety-two patients were randomly assigned into control group(46 cases)for 4-week intervention of both acupuncture and conventional treatment,and observation group(46 cases)for 4-week intervention of Shenqi Taohua Siwu Decoction,Fusui Decoction,acupuncture and conventional treatment.The changes in clinical effects,TCM syndrome scores,serological indices(Glu,GABA,Glu/GABA,Gly,HCY,ASP),nervous function indices(BDNF,NGF,NT-3),NIHSS score,FMA score,MAS score,Barthel score,surface electromyography signals(Hmax,Mmax,Hmax/Mmax)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups demonstrated increased GABA,Gly,nervous function indices,FMA score,Barthel score(P＜0.05),and decreased TCM syndrome scores,Glu,Glu/GABA,HCY,ASP,NIHSS score,MAS score,surface electromyography signals(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with post-ischemic stroke spastic paralysis due to Qi Deficiency and Blood Stasis,Shenqi Taohua Siwu Decoction plus Fusui Decoction combined with acupuncture can safely and effectively improve nerve functions,motor functions,life quality,and reduce TCM syndrome scores,spasticity degree.
