Chemical constituents from the roots of Pfaffia glomerata(Ⅱ)
10.3969/j.issn.1001-1528.2024.05.021
- VernacularTitle:巴西人参根化学成分的研究(Ⅱ)
- Author:
Jin-Cheng HUANG
1
;
Xiao-Qing ZHOU
;
Dong-Mei YAN
;
Li-Ping TANG
;
Hong-Dong LIU
;
Bin LI
Author Information
1. 江西中医药大学院士工作站,江西 南昌 330004
- Keywords:
Pfaffia glomerata(Spreng)Pedersen;
roots;
chemical constituents;
isolation and identification;
sterone
- From:
Chinese Traditional Patent Medicine
2024;46(5):1545-1551
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from the roots of Pfaffia glomerata(Spreng)Pedersen.METHODS The 95%and the 50%ethanol extract from P.glomerata were isolated and purified by silica gel,D101 macroporous resin,sephadex LH-20,polyamide,ODS,preparative HPLC and recrystallization,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Eighteen compounds were isolated and identified as 1,2,4-benzenetriol(1),polypodine B(2),(-)-syringaresinol-4-O-β-D-glucopyranoside(3),poststerone(4),stachysterone B(5),calonysterone(6),taxisterone(7),makisterone C(8),20,22-O-(R-ethylidene)-20-hydroxyecdysone(9),20,22-O-(R-3-methoxycarbonyl)propylidene-20-hydroxyecdysone(10),shidasterone(11),5α-20-hydroxy-ecdysone(12),abutasterone(13),25-hydroxydacryhainansterone(14),methyl-α-D-fructofuranoside(15),methyl-β-D-fructofuranoside(16),chikusetsusaponin Ⅳamethyl ester(17),uridine(18).CONCLUSION Compounds 1-6,8-16,18 are isolated from P.glomerata for the first time,and compounds 1,3-6,8-16,18 are isolated from the genus of Pfaffia for the first time.
