Clinical effects of Danzhi Xiaoyao Powder combined with Hetiao Duren Anshen Acupuncture Method on patients with post-stroke depression
10.3969/j.issn.1001-1528.2024.05.016
- VernacularTitle:丹栀逍遥散联合和调督任安神针刺法对卒中后抑郁患者的临床疗效
- Author:
Wei-Zhi GONG
1
;
Jin DAI
;
Feng LIANG
;
Jian-Li WU
Author Information
1. 黑龙江中医药大学附属第二医院推拿科,黑龙江 哈尔滨 150001
- Keywords:
Danzhi Xiaoyao Powder;
Hetiao Duren Anshen Acupuncture Method;
conventional treatment;
post-stroke depression
- From:
Chinese Traditional Patent Medicine
2024;46(5):1520-1523
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Danzhi Xiaoyao Powder combined with Hetiao Duren Anshen Acupuncture Method on patients with post-stroke depression.METHODS Ninety-eight patients were randomly assigned into control group(49 cases)for 4-week intervention of conventional treatment,and observation group(49 cases)for 4-week intervention of Danzhi Xiaoyao Powder,Hetiao Duren Anshen Acupuncture Method and conventional treatment.The changes in clinical effects,MoCA score,intestinal flora(Enterococcus,Lactobacillus,Escherichia coli,Bifidobacterium),immune function indices(IgM,IgG,IgA),depression status indices(HAMD score,SDS score)and incidence of adverse reactions were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed increased MoCA score,immune function indices(P＜0.05),decreased HAMD score,SDS score(P＜0.05),reduced Enterococcus,Escherichia coli(P＜0.05),and elevated Lactobacillus,Bifidobacterium(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with post-stroke depression,Danzhi Xiaoyao Powder combined with Hetiao Duren Anshen Acupuncture Method can safely and effectively improve cognitive functions,humoral immunities,regulate intestinal flora,and alleviate depression symptoms.
