Guihuang Formula for type Ⅲ prostatitis with damp-heat stasis syndrome in the essence chamber:A clinical trial
10.13263/j.cnki.nja.2024.08.011
- VernacularTitle:归黄方治疗Ⅲ型前列腺炎精室湿热瘀滞证的临床研究
- Author:
Qing-He GAO
1
;
Sheng-Jing LIU
;
Ming ZHAO
;
Zi-Wei ZHAO
;
Bo-Da GUO
Author Information
1. 中国中医科学院西苑医院男科,北京 100091
- Keywords:
chronic prostatitis;
Guihuang Formula;
clinical trial;
essence chamber dampness-heat stasis
- From:
National Journal of Andrology
2024;30(8):738-743
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the efficacy and safety of Guihuang Formula(GHF)in the treatment of type Ⅲ prostatitis with the syndrome of damp-heat stasis in the essence chamber.Methods:This study included 120 cases of type Ⅲ prostatitis with damp-heat stasis syndrome in the essence chamber,which were randomly and equally divided into a GHF and a control group,the for-mer treated with GHF and the latter with Tamsulosin Hydrochloride Sustained-Release Capsules,both for 6 successive weeks.We fol-lowed up the patients for 4 weeks,recorded the NIH-CPSI,TCM symptom scores,and results of prostatic fluid routine,blood and u-rine routine,liver and kidney function and electrocardiogram examinations,and compared them between the two groups of patients be-fore and after treatment.Results:Compared with the baseline,the total NIH-CPSI scores were significantly decreased in both the GHF and control groups after 6 weeks of treatment,even more significantly in the former group(28.34±9.23 vs 6.78±3.53,P＜0.05)than in the latter(27.81±8.28 vs 14.48±4.27,P＜0.05),so were the scores on pain,voiding symptoms,quality of life(QOL)impact,TCM symptoms and WBC count(all P＜0.05),while the number of lecithin bodies remarkably increased(P＜0.05).There were statically significant differences in the above parameters at 4,6 and 10 weeks of medication(P＜0.05),but not at 2 weeks(P＞0.05).No obvious abnormalities or adverse reactions were observed in either of the two groups during the treatment.Conclusion:Guihuang Formula is safe and effective in the treatment of type Ⅲ prostatitis with the syndrome of damp-heat stasis in the essence chamber.
