HoLEP versus TURP in improving the prostate function,oxidative stress indicators and sexual function of the patient with BPH
10.13263/j.cnki.nja.2024.08.007
- VernacularTitle:经尿道前列腺钬激光剜除术与经尿道前列腺电切术对良性前列腺增生患者前列腺功能、氧化应激指标及性功能的影响比较
- Author:
Xiao-Hui WEI
1
;
Yi-Bo GU
Author Information
1. 常州市妇幼保健院泌尿外科,江苏常州 213000
- Keywords:
holmium laser enucleation of the prostate;
transurethral resection of the prostate;
benign prostatic hyperplasia;
prostate function
- From:
National Journal of Andrology
2024;30(8):717-721
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the effect of holmium laser enucleation of the prostate(HoLEP)with that of transurethral resection of the prostate(TURP)on the prostate function,oxidative stress indicators and sexual function of the patient with BPH.Methods:We randomly assigned 100 BPH patients to receive HoLEP(n=50)or TURP(n=50)in our hospital from June 2021 to June 2023,and compared the perioperative parameters,prostate function,oxidative stress indicators,sexual function and postopera-tive complications between the two groups.Results:The intraoperative blood loss was significantly less and the time of catheterization,bladder irrigation and hospital stay remarkably shorter in the HoLEP than in the TURP group(P＜0.05).The postoperative IPSS and quality of life(QOL)scores were markedly lower,level of superoxide dismutase(SOD)higher,content of malondialdehyde(MDA)and total antioxidant capacity(T-AOC)lower,IIEF-5 and Erection Hardness Grading Scale(EHGS)scores higher,and incidence of postoperative complications lower in the HoLEP than in the TURP group(all P＜0.05).Conclusion:HoLEP is superior to TURP in improving the prostate function,oxidative stress indicators and sexual function of the patient with BPH.
