Prediction of triglyceride-rich lipoprotein cholesterol for coronary artery lesions in elderly patients and evaluation of its predictive value
10.3969/j.issn.1009-0126.2024.05.011
- VernacularTitle:富含三酰甘油的脂蛋白胆固醇对老年患者冠状动脉病变的预测及评估价值分析
- Author:
Wei QI
1
;
Hongliang CONG
Author Information
1. 300222 天津大学胸科医院心内科天津市心血管病研究所
- Keywords:
coronary artery disease;
lipoproteins;
forecasting;
logistic models;
triglyceride-rich lipo-protein
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(5):527-530
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between triacylglycerol-rich lipoprotein choles-terol(TRL-C)level and the severity of coronary artery disease in elderly patients with coronary heart disease(CHD).Methods A total of 220 elderly CHD patients who underwent coronary an-giography in our hospital from January 1 to December 31,2020 were enrolled in this study.They were divided into mild coronary artery disease group(SYNTAX score 1-22,158 cases)and mod-erate to severe coronary artery disease group(SYNTAX score ≥23,62 cases).Logistic regression analysis and ROC curve analysis were used.Results Compared with the mild coronary artery dis-ease group,the moderate and severe coronary artery disease group had significantly lower albu-min,apolipoprotein(Apo)A and platelet count,while increased cTnT,NT-proBNP and TRL-C levels(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that TRL-C was a risk factor(OR=4.450,95％CI:1.572-12.599,P=0.005),while albumin was a protective factor for coronary artery disease(OR=0.880,95％CI:0.794-0.977,P=0.016).ROC curve analysis indi-cated that the AUC value of TRL-C for diagnosing moderate to severe coronary lesions was 0.655(95％CI:0.580-0.731).Conclusion TRL-C has a predictive value for the severity of coronary artery disease in elderly CHD patients,and has a predictive value for moderate to severe coronary artery disease.
