Overview of new diagnostic markers for chronic hepatitis B
10.3760/cma.j.issn.1674-2397.2024.02.002
- VernacularTitle:慢性乙型肝炎新型诊断标志物的研发概况
- Author:
Yilin MA
1
Author Information
1. 浙江大学医学院附属第一医院感染病科 传染病重症诊治全国重点实验室 国家感染性疾病临床医学研究中心，杭州 310003
- Keywords:
Chronic hepatitis B;
New diagnostic markers;
Covalently closed circular DNA（cccDNA）;
HBV RNA;
HBcrAg;
Anti-HBc
- From:
Chinese Journal of Clinical Infectious Diseases
2024;17(2):93-98
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B has become a global disease that seriously threatens human health，and it is also one of the widespread and serous infectious diseases in China. According to China Health Statistical Yearbook（2022），the incidence rate of hepatitis B in China is 69.25/100 000 in 2021. This article elaborates the the correlation between viral replication and related novel diagnostic markers of hepatitis virus，the clinical significance and the advances in detection technology of these markers，to provide information for clinician in the field of infectious diseases. It is suggested that the testing for novel hepatitis markers should be expanded in relevant institutions，which will be helpful for clinical diagnosis and antiviral therapy evaluation，to achieve the World Health Organization's goal of increasing hepatitis B diagnosis rate to 90% by 2030.
