New perspectives on FAPI PET: advances in cardiovascular disease
10.3760/cma.j.cn321828-20240303-00084
- VernacularTitle:FAPI PET新视角：在心血管疾病中的应用进展
- Author:
Feng YIN
1
;
Jun ZHAO
Author Information
1. 同济大学附属东方医院核医学科，上海 200120
- Keywords:
Cardiovascular diseases;
Antagonists and inhibitors;
Membrane proteins;
Fibroblasts;
Positron-emission tomography;
Trends
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2024;44(11):693-696
- CountryChina
- Language:Chinese
-
Abstract:
Fibroblast activating protein (FAP) is a membrane-anchored peptidase. Since its development in 2019, PET imaging of FAP inhibitor (FAPI) has been widely used in the diagnosis, staging, efficacy evaluation and prognosis of malignant tumors. The accidental discovery of FAPI uptake in the cardiovascular system in the application of malignant tumors has led to the consideration of the diagnostic and prognostic value of FAPI imaging in cardiovascular diseases. This article makes a relevant summary.
