Advances in postmastectomy radiotherapy in breast cancer patients with immediate breast reconstruction
10.3760/cma.j.cn113030-20240207-00053
- VernacularTitle:乳腺癌即刻乳房重建术后放疗的研究进展
- Author:
Mingjiu WANG
1
;
Shulian WANG
Author Information
1. 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科，北京 100021
- Keywords:
Breast neoplasms;
Mastectomy;
Breast reconstruction;
Radiotherapy
- From:
Chinese Journal of Radiation Oncology
2024;33(6):567-571
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer is a female malignant tumor with the highest incidence rate worldwide, and surgery-based comprehensive treatment is the main treatment mode. Radiotherapy after total mastectomy can improve the regional control rate and survival rate of high-risk patients with lymph node positive breast cancer. With the improvement of survival, patients have increasing demand for the quality of life and cosmetic effects. Breast reconstruction after total mastectomy improves the quality of life of patients. The utilization of immediate breast reconstruction following mastectomy in breast cancer has been steadily increasing, which poses significant challenges for adjuvant radiotherapy if indicated. Radiotherapy is known to increase the risk of complications in the reconstructed breast, and the type of reconstruction and heterogeneity of radiotherapy can impact the outcomes of the reconstructed breast. In this article, we briefly review the principal factors influencing the complication risk of reconstructed breast after radiotherapy, and the appropriate radiation target delineation, dose fractionation and techniques. Furthermore, we provide an overview of the research in preoperative radiotherapy in the setting of immediate breast reconstruction.
