Advances in research on treatment-associated pneumonitis in lung cancer patients treated with radiation combined with immunotherapy

VernacularTitle:肺癌患者接受放疗和免疫治疗后引发治疗相关性肺炎的研究进展
Author: Youjia WANG ¹ ; Guang HAN
Author Information

1. 华中科技大学同济医学院附属湖北省肿瘤医院放疗中心，武汉　430000
Keywords: Lung cancer; Radiotherapy; Immune checkpoint inhibitor; Radiation-induced immune-related pneumonitis
From: Chinese Journal of Radiological Medicine and Protection 2024;44(8):711-717
CountryChina
Language:Chinese
Abstract: Radiotherapy and immunotherapy prove significant for cancer treatment presently. Despite therapeutic effects, they carry risks of adverse reactions. The survival rates and quality of life of patients with thoracic malignancies frequently fail to fulfill expectations after they receive radiotherapy combined with immunotherapy. A major reason for this is the occurrence of treatment-associated pneumonitis. To gain a deeper understanding of the pneumonitis induced by radiotherapy combined with immunotherapy for lung cancer, this paper reviews the pathogenesis, incidence, risk factors, differential diagnosis, and treatment of such pneumonitis.