Advances in research on the application of the expression analysis of radiation-responsive genes to biological dose estimation
10.3760/cma.j.cn112271-20240313-00090
- VernacularTitle:辐射敏感基因表达分析用于生物剂量估算的研究进展
- Author:
Shuang LI
1
;
Qingjie LIU
Author Information
1. 中国疾病预防控制中心辐射防护与核安全医学所 辐射防护与核应急中国疾病预防控制中心重点实验室，北京 100088
- Keywords:
Ionizing radiation;
Gene expression;
Biodosimetry;
Dose estimation
- From:
Chinese Journal of Radiological Medicine and Protection
2024;44(8):704-710
- CountryChina
- Language:Chinese
-
Abstract:
Following large-scale nuclear and radiological emergencies, the accurate estimation of radiation doses can provide a crucial scientific basis for subsequent medical treatment and prognosis of acute radiation injury. In recent years, the expression analysis of radiation-responsive genes has emerged as an effective approach to dose classification and clinical risk prediction for a large population owing to its high speed and high throughput. This paper reviews the advances in research on the application of the expression analysis to biological dose estimation, with a view to promoting the popularization of this technology and to further enhancing China′s capacity for radiation dose estimation.
