Research progress on anti-inflammatory effect and molecular mechanism of Artemisia dracunculus
10.3969/j.issn.1008-9691.2024.04.027
- VernacularTitle:椒蒿的抗炎作用及其分子机制研究进展
- Author:
Yifei XU
1
;
Lei ZHAO
;
Jie ZHEN
;
Guomin ZHAO
;
Wei CHEN
Author Information
1. 首都医科大学附属北京世纪坛医院重症医学科,北京 100038
- Keywords:
Artemisia dracunculus;
Anti-inflammatory effect;
Immune cell;
Inflammatory mediator;
Signaling pathway;
Mechanism
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2024;31(4):508-512
- CountryChina
- Language:Chinese
-
Abstract:
Inflammation is the pathological basis of many diseases,which can infect locally or act on the whole body,and is closely related to the pathogenesis of many diseases.In recent years,in the background of more and more traditional anti-inflammatory drugs showing adverse reactions,scholars have been exploring the use of traditional Chinese medicine in the ascendant.As an herb in the Asteraceae(daisy)family,Artemisia dracunculus possesses low toxicity and a wide range of uses and can be applied to the regulation of metabolism,analgesia,antidepressant,antioxidant,immune regulation,antibacterial,anti-inflammatory,antiparasitic,and other treatment of a variety of diseases.In-depth studies have revealed that the therapeutic effects and potential of Artemisia dracunculus for a variety of diseases are closely related to its anti-inflammatory mechanism.This article will summarize the relevant literature in recent years and review the research progress of the mechanism of Artemisia dracunculus on the regulation of immune cells and inflammatory factors,as well as its mediation of inflammation-related signaling pathways,intending to provide theoretical references for future application of Artemisia dracunculus in clinical trials and treatments.
