Significance of biomarkers associated in sepsis-associated acute kidney injury
10.3969/j.issn.1008-9691.2024.01.025
- VernacularTitle:生物标志物在脓毒症相关急性肾损伤中的应用
- Author:
Yiping LIU
1
;
Xiaoshu LIU
Author Information
1. 电子科技大学医学院,四川成都 610054;四川省医学科学院,四川省人民医院呼吸与危重症医学科,四川成都 610072
- Keywords:
Sepsis;
Sepsis-associated acute kidney injury;
Biomarkers;
Creatinine;
Neutrophil gelatinase associated lipocalin
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2024;31(1):112-116
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis associated acute kidney injury(SA-AKI)is one of the common complications of sepsis,a syndrome of acute functional and organ damage associated with long-term adverse outcomes due to sepsis,and its incidence is gradually increasing and its mortality rate is much higher than that of sepsis alone.Early identification of SA-AKI and prediction of disease progression using biomarkers and corresponding interventions are essential to reduce the risk of death and long-term sequelae of SA-AKI.Until now,few biomarkers have been proposed to specifically identify SA-AKI,clinical use of biomarkers associated with acute kidney injury(AKI)to identify the occurrence or predict the progression of SA-AKI is essential to understand the differences between AKI-associated biomarkers produced or changed in AKI and SA-AKI,and to evaluate the role of AKI-associated biomarkers in identifying SA-AKI related biomarkers in identifying the occurrence and predicting the progression of SA-AKI is a key aspect.This article outlines the differences between AKI-related biomarkers in the occurrence and progression of AKI and SA-AKI,and provides a reference for identifying biomarkers for the occurrence and predicting the progression of SA-AKI.
