Role and Clinical Prospects of Mesenchymal Stem Cells and Their Derived Exosomes in Chronic Obstructive Pulmonary Disease
10.3760/cma.j.cn101721-20240616-00185
- VernacularTitle:间充质干细胞及其衍生外泌体在慢性阻塞性肺疾病中的作用与临床前景
- Author:
Ruiying WANG
1
;
Shuang WEI
;
Xiansheng LIU
Author Information
1. 山西白求恩医院 山西医学科学院 同济山西医院 山西医科大学第三医院呼吸与危重症医学科，太原 030032
- Keywords:
Chronic obstructive pulmonary disease;
Mesenchymal stem cells;
Exosome
- From:
Clinical Medicine of China
2024;40(6):465-473
- CountryChina
- Language:Chinese
-
Abstract:
Chronic obstructive pulmonary disease (COPD) is a chronic, heterogeneous inflammatory disease with high prevalence and mortality rate. Although current treatments can relieve symptoms, they cannot prevent further decline in lung function. With the development of stem cell therapy, mesenchymal stem cells and their extracellular vesicles have received widespread attention for their anti-inflammatory, immune regulation, tissue regeneration and repair functions, aging, and other applications in the treatment of lung diseases. This article reviews the role and clinical application prospects of mesenchymal stem cells and their derived exosomes in chronic obstructive pulmonary disease and its complications.
