Predictive value of contrast-enhanced ultrasound for the invasiveness of clear cell renal cell carcinoma
10.3969/j.issn.1672-8270.2024.08.015
- VernacularTitle:超声造影对肾透明细胞癌侵袭性的预测价值
- Author:
Ruoxuan FENG
1
;
Linxue QIAN
Author Information
1. 首都医科大学附属北京友谊医院超声科 北京 100050
- Keywords:
Contrast-enhanced ultrasound;
Clear cell renal cell carcinoma;
Microvessel density;
Prediction
- From:
China Medical Equipment
2024;21(8):80-83
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the relationship between the characteristics of contrast-enhanced ultrasound and the invasiveness of clear cell renal cell carcinoma.Methods:A total of 63 patients with clear cell renal cell carcinoma who were confirmed by surgical pathology of Beijing Friendship Hospital of Capital Medical University from January 2014 to November 2021 were selected retrospectively.According to the results of pathology,they were divided into an invasive group(11 cases)and a non-invasive group(52 cases).The features of contrast-enhanced ultrasound,which included perfusion time,regression time,enhancement degree,enhancement mode,pseudocapsule and perfusion defect,were analyzed.Results:The contrast-enhanced ultrasound of clear cell renal cell carcinoma mostly showed fast perfusion,slow regression,high enhancement and uneven enhancement,while there were no significant differences between the two groups(P>0.05).In the comparison of the features of routine ultrasound of invasive group and non-invasive group,there was significant difference in the size of tumor,and the medians of the maximum diameters of them were respectively 6.60(3.30,8.80)cm and 3.60(2.63,4.88)cm.The maximum diameter of invasive group was larger,and there was significant difference between the two groups(Z=-2.346,P<0.05).The ratio of perfusion defect of invasive group was significantly higher than that of non-invasive group,and the ratio of pseudocapsule of tumor of non-invasive group was significantly higher than that of invasive group,and there were significant differences between the two groups(x2=9.450,5.839,P<0.05).Conclusion:A larger diameter of the tumor and a higher ratio of perfusion defect prefer to invasive clear cell renal cell carcinoma,and the features of the contrast-enhanced ultrasound will contribute to predict the invasiveness of clear cell renal cell carcinoma before surgery,which may provide the basis for clinical treatment.
