Correlations of iterative decomposition of water and fat with echo asymmetry and the least squares estimation quantification sequence fat parameters and clinical data in patients with non-alcoholic fatty liver disease
10.13929/j.issn.1003-3289.2024.11.017
- VernacularTitle:非酒精性脂肪性肝病患者定量非对称回波最小二乘估算法迭代水脂分离序列脂肪参数与临床资料的相关性
- Author:
Xue WU
1
;
Jian SHU
;
Pinxiong LI
;
Fan MIN
Author Information
1. 西南医科大学附属医院放射科,四川泸州 646000;内江市第二人民医院医学影像科,四川内江 641000
- Keywords:
non-alcoholic fatty liver disease;
adipose tissue;
magnetic resonance imaging;
water-fat separation
- From:
Chinese Journal of Medical Imaging Technology
2024;40(11):1715-1719
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the correlations of iterative decomposition of water and fat with echo asymmetry and the least squares estimation quantification sequence(IDEAL-IQ)fat parameters and clinical data in patients with non-alcoholic fatty liver disease(NAFLD).Methods Totally 42 NAFLD patients were prospectively enrolled and divided into lean group(n=9),overweight group(n=19)and obese group(n=14)based on body mass index.Clinical data and IDEAL-IQ fat parameters(hepatic fat fraction[HFF],abdominal visceral adipose tissue[VAT]and subcutaneous adipose tissue[SAT]volumes)were compared among 3 groups and between each 2 groups,and the correlations of HFF,abdominal VAT and SAT volumes and clinical data were analyzed.Results Significant differences of abdominal VAT and SAT volumes were found among 3 groups(both P＜0.05).Abdominal VAT volume in obese group was significantly higher than that in lean and overweight groups(both P＜0.05),and significant differences of abdominal SAT volume were found between each 2 groups(all P＜0.05).Meanwhile,significant differences of abdominal VAT and SAT volumes were found between male and female patients(t=2.559,-2.606,both P＜0.05),but not of HFF(t=1.332,P=0.191).HFF was positively correlated with age,systolic blood pressure(SBP),diastolic blood pressure(DBP)and glutamic-oxaloacetic transaminase(GOT)in NAFLD patients(r=0.418,0.408,0.370,0.340,all P＜0.05).Conclusion In NAFLD patients,HFF was related to age,SBP,DBP and GOT,while abdominal VAT and SAT volumes were related to gender.
