Effect of Extravascular Irradiation with Weak Laser on Treating Hypertension,Hyperglycemia, and Hyperlipidemia
10.3881/j.issn.1000-503X.2018.01.013
- VernacularTitle:弱激光血管外照射降低血压、血脂和血糖的疗效
- Author:
Huijuan YIN
1
;
Zhuying CHEN
;
Yingxin LI
;
Zengwu WANG
;
Xinfeng GUO
;
Xiaoguang WU
Author Information
1. 中国医学科学院北京协和医学院生物医学工程研究所激光医学实验室
- Keywords:
weak laser external irradiation;
hypertension;
hyperglycemia;
hyperlipidemia;
questionnaire survey
- From:
Acta Academiae Medicinae Sinicae
2018;40(1):83-90
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of weak laser on treating hypertension,hyperglycemia,and hyperlipidemia.Methods A questionnaire-based survey was carrried out nationwide among the users of wrist-band weak laser irradiation.Changes in blood pressure,blood lipids,and blood glucose were analyzed before and after treatment.The influencial factors of antihypertensive effect of weak laser irradiation were analyzed by univariate and multivariate linear regression method.Results Questionnaire forms were returned from 5801 users,among whom 1335 patients with hypertension,180 patients with hyperglycemia,and 129 patients with hyperlipidemia entered the final analysis.After treatment,systolic blood pressure (SBP) (t =53.16,P ＜0.001),diastolic blood pressure (DBP) (t =34.17,P ＜ 0.001),triglycerides (TG) (t =7.87,P ＜0.001),total cholesterol (TC) (t =8.78,P ＜ 0.001),and fasting blood glucose (FBG) (t =11.64,P ＜0.001) were significantly decreased (compared with pre-treatment levels).Compared with the baseline,SBP,DBP,TG,TC and FBG fell by 23.3 mmHg (14.50％) (1 mmHg =0.133 kPa),10.6 mmHg (11.40％),0.86mmol/L (28.70％),1.11 mmol/L (18.00％),and 3.64 mmol/L (34.40％).The decrease of DBP in patients without insomnia was significantly higher than that in insomnia patients (F =9.54,P =0.00),and the decrease of DBP in non-drinkers was significantly higher than that in drinkers (F =5.08,P =0.02).The decrease of TG was significantly higher in males than in females (Z =2.48,P =0.01),in patients with mental stress than in those without stress (Z =-2.16,P =0.03),and in smokers than non-smokers (Z =-2.17,P =0.03).The median irradation time was 616 d (1-5479d).According to the irradiation time,the patients were further divided into four group:＜ 272d,272-698d,699-1435d,and ＞ 1437d.The SBP declined by (-22.25±16.22),(-21.59±15.24),(-24.96±16.82),and (-24.66±15.88) mmHg,respectively,in these four groups (F =3.55,P =0.01).Multivariate linear regression analysis showed that the influencial factors of SBP variation included gender (β =-0.08,P =0.0178) and irradiation time (β =-0.09,P =0.0016).The factors influencing the change of DBP were gender (β =-0.10,P =0.0039),insomnia (β =0.09,P =0.0015),and alcohol consumption (β =0.10,P =0.0033).Conclusion Long-time weak laser external irradiation has certain effectiveness in treating hypertension,hyperglycemia,and hyperlipidemia.
