The mechanism of panapoptosis and clinical research progress

VernacularTitle:泛凋亡机制与临床研究进展
Author: Xin WANG ¹ ; Feng ZHU ; Zhonghua FU
Author Information

1. 南昌大学第一附属医院烧伤整形与创面修复医学中心，南昌　330000
Keywords: Panoptosis; Pyroptosis; Apoptosis; Necroptosis
From: Journal of Chinese Physician 2024;26(11):1739-1743
CountryChina
Language:Chinese
Abstract: Panapoptosis is a new focus of current research, which is essentially the inflammatory programmed cell death, with the common characteristics of pyrodeath, apoptosis and necrotic apoptosis. Panapoptosis is closely related to many diseases, such as infectious diseases, tumors, neurodegenerative diseases and so on. As a pathway of recognition and activation by the immune system, panapoptosis plays an important role in controlling the spread of inflammation and disease progression, although the specific regulatory mechanism is not yet clear. This review aims to explore the role of panapoptosis in the pathogenesis and development of cellular inflammation and diseases, and seek potential intervention targets to provide new strategies for clinical disease treatment.