Research progress on the mechanism of micro-RNA in inflammation and fibrosis of endometriosis

VernacularTitle:microRNA在子宫内膜异位症炎症和纤维化中的作用机制研究进展
Author: Hui YANG ¹ ; Cuiping YU ; Bingbing LI
Author Information

1. 济宁医学院中西医结合学院，济宁　272000
Keywords: MicroRNAs; Endometriosis; Inflammation; Fibrosis
From: Journal of Chinese Physician 2024;26(4):617-621
CountryChina
Language:Chinese
Abstract: Endometriosis (EM) is a common gynecological disease in women of childbearing age, and its pathogenesis is currently not fully understood. EM are a chronic inflammatory response, and long-term inflammatory exudation can lead to the production of fibrotic adhesions. Inflammatory response and fibrosis formation are the main pathological features of EM, as well as the main causes of pain and infertility. Research has shown that there are certain differentially expressed microRNAs (miRNAs) in EM that participate in inflammation and fibrosis processes and play important regulatory roles. This article reviews the mechanism of miRNA in the inflammatory and fibrotic pathological processes of EM, aiming to find new directions and ideas for exploring the pathogenesis and diagnosis and treatment of EM.