Analysis of risk factors for stent occlusion after iliac vein stenting and construction of a clinical prediction model
10.3969/j.issn.1009-9905.2024.08.009
- VernacularTitle:髂静脉支架置入术后支架闭塞的危险因素分析及临床预测模型构建
- Author:
Lei WEI
1
;
XING JIN
Author Information
1. 山东省立第三医院 心脏大血管外科(山东 济南 250031)
- Keywords:
Iliac vein stenosis;
Iliac vein stent placement;
Iliac vein occlusion;
Risk factors;
Prediction model
- From:
Chinese Journal of Current Advances in General Surgery
2024;27(8):633-638
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify the risk factors associated with stent occlusion following iliac vein stenting and develop a clinical prediction model.Methods:Clinical data from 150 pa-tients who underwent iliac vein stenting were collected.Based on the patency of the iliac vein stent within one year post-surgery,patients were categorized into an occlusion group(50 patients)and a control group(100 patients).Univariate analysis was conducted to compare and select single factors with significant differences between groups,which were then included in binary logistic regression analysis to identify independent risk factors for stent occlusion after iliac vein stent placement.The accuracy of the prediction model was assessed through calibration curve plotting,consistency index calculation,receiver operating characteristic(ROC)curve analysis,as well as de-cision curve analysis.Results:Statistically significant differences were observed in gender,etiol-ogy,comorbid hypertension and arteriovenous fistula status,C-reactive protein(CRP)levels,acti-vated partial thromboplastin time(APTT),total stent length,and external iliac vein recanalization rate between the two groups(P＜0.05).Logistic regression results revealed that gender,etiology,arteriovenous fistula status APTT level and external iliac vein recanalization rate were independent risk factors for iliac vein stent occlusion(P＜0.05).These variables were used to construct a predic-tion model along with a corresponding scoring system.The consistency index was calculated at 0.865;internal validation yielded a consistency index of 0.861.The calibration curve of the model closely aligned with actual observations.The area under the ROC curve for verifying model accu-racy was determined to be 0.859 indicating good clinical applicability.Conclusion:Gender,etiol-ogy,arteriovenous fistula status,APTT level,and external iliac vein recanalization rate are identified as independent risk factors influencing stent occlusion following iliac vein stenting and clinical pre-diction model denonstrated good accuracy.
