Application of nomogram model based on sonographic fea-tures in the differential diagnosis of breast ductal carcinoma in situ and intraductal papilloma
10.3969/j.issn.1009-9905.2024.06.005
- VernacularTitle:超声特征列线图模型在乳腺导管原位癌和导管内乳头状瘤鉴别诊断中的应用
- Author:
Yu-Qing LONG
1
;
Hai-Yan WU
;
Yuan LI
;
Xing-Chen ZHOU
;
Mei WU
Author Information
1. 山东大学第二医院医学影像中心超声科(山东 济南 250033)
- Keywords:
Breast neoplasm;
Breast ductal carcinoma in situ,intraductal papilloma;
Ultrasound features;
Nomogram
- From:
Chinese Journal of Current Advances in General Surgery
2024;27(6):447-452
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the clinical and ultrasonographic characteristics of ductal carcinoma in situ(DCIS)and intraductal papilloma(IDP),and to construct a nomogram predictive model for DCIS and IDP.Methods:We selected data from 156 cases(212 nodules)of DCIS and 158 cases(238 nodules)of IDP confirmed by pathology.Through univariate and multivariate analy-ses,we evaluated the influencing factors of ultrasonic diagnosis of DCIS and established a diagnos-tic model to clarify the value of each ultrasonographic sign in diagnosis.Results:The univariate analysis showed statistically significant differences between the two groups in terms of age,medi-cal history,nodule long diameter,volume,margin,posterior echo,calcification,color Doppler flow imaging(CDFI),and resistance index(R/)(P＜0.05).The multivariate logistic regression analysis showed that the absence of abnormal ducts around the nodule,posterior echo attenuation,pres-ence of microcalcifications,and RI≥0.70,tend to indicate DCIS,while simple dilation or lack of blood supply of the duct around the nodule tend to indicate IDP.These indicators were included in the nomogram model,which showed high predictive performance,calibration,and clinical value in both the training and validation sets.Conclusion:The nomogram model based on sonographic fea-tures can easily distinguish DCIS from IDP.The presence of abnormal ducts around the nodule,posterior echo attenuation,presence of microcalcifications,and RI＞0.70 should raise suspicion for DCIS.
