Impact of flash glucose monitoring system on glycemic control in pregnant women with type 2 diabetes mellitus
10.3969/j.issn.1006-6187.2024.06.004
- VernacularTitle:扫描式葡萄糖监测在2型糖尿病妊娠患者管理中的作用
- Author:
Zhaoyan ZHANG
1
;
Xiuqing LOU
;
Xuefang WANG
;
Yue ZHAO
;
Xudong SU
Author Information
1. 252000 聊城市妇幼保健院妇产科
- Keywords:
Diabetes mellitus,type 2;
Pregnant;
Flash glucose monitoring
- From:
Chinese Journal of Diabetes
2024;32(6):418-422
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the impact of flash glucose monitoring(FGM)system on glycemic control and adverse pregnancy outcome in pregnant women with type 2 diabetes mellitus(T2DM).Methods This prospective,open-label,randomized,controlled clinical trial involved 109 women with T2DM at 16～18 weeks of gestation who visited Liaocheng People's hospital and Liaocheng Women and Children Hospital from June 2018 to June 2022.They were randomly assigned to FGM group(54 cases)and control group(55 cases).The FGM group wore FGM at 20,24,28 and 32 weeks of pregnancy respectively.The Con group underwent self-monitoring of blood glucose(SMBG).Both groups adjusted insulin doses based on blood glucose monitoring results.HbA1c was measured at 18 weeks and 36 weeks of pregnancy.Information related to adverse pregnancy outcomes was compared between the two groups.Results Fasting and postprandial glucose and HbA1c were significantly lower in FGM group compared with con group(P<0.05).Neonatal hypoglycemia was significantly lower in FGM group(P<0.05).There was no difference between the two groups in terms of BMI,insulin dose,gestational week of delivery,Apgar score,neonatal weight and the incidence of preeclampsia,premature delivery,polyhydramnios,cesarean section,SGA,macrosomia and postpartum hemorrhage(P>0.05).Time in range(TIR),time below range(TBR),time above range(TAR),and mean amplitude of glucose excursion(MAGE)were significantly improved at 32 weeks compared to 20 weeks in FGM group(P<0.05).Conclusions Repeated intermittent use of FGM in pregnant women with T2DM could reduce the blood glucose level and the incidence of neonatal hypoglycemia.
