Research Progress on Role of Long Non-Coding RNA in Occurrence and Development of Acute Myeloid Leukemia——Review
10.19746/j.cnki.issn1009-2137.2024.03.051
- VernacularTitle:长链非编码RNA在急性髓细胞白血病发生发展中作用的研究进展
- Author:
Xiao-Shi LU
1
;
Xin-Qi WANG
;
Ying-Nan DU
;
Ji-Hong ZHANG
Author Information
1. 中国医科大学第四临床学院,辽宁沈阳 110122
- Keywords:
acute myeloid leukemia;
long non-coding RNA;
tumor promoter;
tumor suppressor;
drug resistance;
prognosis
- From:
Journal of Experimental Hematology
2024;32(3):974-978
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the importance of long non-coding RNA(lncRNA)in acute myeloid leukemia(AML)has attracted wide attention.Among them,lncRNAs that play a role in promoting cancer mainly include HOTAIR,UCA1,H19,ITGB2-AS1 and some genes of SNHG family,while in tumor suppression mainly include H22954,NEAT1,SNHG4,LINC01128,etc.This article reviews the role of lncRNAs in the occurrence and development of AML,as well as those related to AML resistance and prognosis assessment,so as to provide a theoretical basis for the diagnosis and prognosis analysis of AML.
