Research progress in the application of single-cell sequencing technology in multiple sclerosis
10.3969/j.issn.1671-7856.2024.10.019
- VernacularTitle:单细胞测序技术在多发性硬化研究中的应用进展
- Author:
Zhihong MA
1
;
Lihong ZHANG
;
Yuan CAO
;
Ming CHENG
Author Information
1. 中国人民解放军联勤保障部队第九六○医院基础医学实验室,济南 250031
- Keywords:
multiple sclerosis;
single-cell sequencing;
central nervous system;
review
- From:
Chinese Journal of Comparative Medicine
2024;34(10):161-168
- CountryChina
- Language:Chinese
-
Abstract:
Multiple sclerosis(MS)is a chronic autoimmune disease of the central nervous system characterized by neuroinflammation and neurodegeneration.The pathogenesis of the disease is complex,and involves various central nervous system and peripheral cells.Single-cell sequencing has recently been increasingly applied in the study of neurological disorders,leading to important advances in our understanding of intercellular heterogeneity,disease development mechanisms,and treatment strategies.This review summarizes research progress in single-cell sequencing and its applications in MS.
