Lipidomics driven biomarker discovery in chronic lung disease
10.3969/j.issn.1671-7856.2024.07.015
- VernacularTitle:脂质组学在慢性肺部疾病生物标志物发现中的应用
- Author:
Ang ZHANG
1
;
Yan DU
;
Yang XIE
;
Xinguang LIU
Author Information
1. 河南中医药大学呼吸疾病中医药防治省部共建协同创新中心,郑州 450046;河南省中医药防治呼吸病重点实验室,郑州 450046
- Keywords:
lipidomics;
chronic obstructive pulmonary disease;
asthma;
idiopathic pulmonary fibrosis;
biomarkers;
traditional Chinese medicine
- From:
Chinese Journal of Comparative Medicine
2024;34(7):131-141
- CountryChina
- Language:Chinese
-
Abstract:
Chronic lung diseases(CLD)include chronic obstructive pulmonary disease,asthma,and idiopathic pulmonary fibrosis.Studies have shown that CLD are closely related to disorders in lipid metabolism.Therefore,lipids,as biomarkers of CLD,may be of great value in the diagnosis,prevention,and monitoring of disease treatment.This review discusses lipidomics from four major aspects:the technical methods of lipidomics,the selection of clinical samples for lipidomics,the discovery of biomarkers for CLD,and the differentiation of traditional Chinese medicine syndromes from CLD.
