Research progress in Brucella main outer membrane proteins
10.3969/j.issn.1002-2694.2024.00.137
- VernacularTitle:布鲁氏菌主要外膜蛋白研究进展
- Author:
Xue-Qiang XIN
1
;
Tong TONG
;
Yu-Jin WANG
;
Yu-Jie SHENG
;
Zheng-Zhong XU
;
Xiang CHEN
Author Information
1. 扬州大学江苏省人兽共患病学重点实验室/江苏省动物重要疫病与人兽共患病防控协同创新中心,扬州 225009
- Keywords:
Brucella;
outer membrane proteins;
antigenic properties
- From:
Chinese Journal of Zoonoses
2024;40(9):872-879
- CountryChina
- Language:Chinese
-
Abstract:
Brucellosis,a worldwide epidemic bacterial zoonotic infectious disease caused by bacteria of the genus Brucella,jeopardizes livestock production and poses a major threat to public health safety.Among the various components of Brucella,the outer membrane proteins play crucial roles as the primary immune and protective antigens.These proteins are closely asso-ciated with Brucella's virulence,regulation of the immune response,and ability to survive and multiply within host cells.This article summarizes recent research progress in the primary outer membrane proteins of Brucella,and offers a synthesized view of the current knowledge landscape.Understanding the antigenic characteristics of Brucella outer membrane proteins may sub-stantially contribute to the establishment of new diagnostic methods and the design of new vaccines,thus potentially leading to more effective prevention strategies against brucellosis.The review provides a reference for future studies and may aid in brucel-losis control efforts.
