Epidemiologic and clinical characterization of tick-borne diseases in an infectious disease hospital in Beijing over the past decade
10.3969/j.issn.1002-2694.2024.00.057
- VernacularTitle:北京市某传染病医院近十年蜱传疾病流行病学及临床特征分析
- Author:
Zi-Bo FAN
1
;
Xu GAO
;
Yuan-Yuan ZHANG
;
Zhi-Hai CHEN
;
Wei ZHANG
Author Information
1. 首都医科大学附属北京地坛医院感染性疾病诊疗中心,北京 100015;国家传染病医学中心,首都医科大学附属北京地坛医院,北京 100015;传染病溯源预警与智能决策全国重点实验室,北京 100015
- Keywords:
tick-borne diseases;
severe fever with thrombocytopenia syndrome;
Lyme disease;
rickettsiosis;
epidemiology;
clinical characteristics
- From:
Chinese Journal of Zoonoses
2024;40(4):315-322
- CountryChina
- Language:Chinese
-
Abstract:
Epidemiological data and clinical characteristics of patients with tick-borne diseases were analyzed to improve diagnosis and treatment outcomes.The data of 32 patients(epidemiology and clinical characteristics)treated for tick-borne diseases at Beijing Ditan Hospital from January 2013 to June 2023 were retrospectively reviewed.Of the 32 patients,17 were diagnosed with severe fever with thrombocytopenia syndrome(SFTS),5 with Lyme disease,and 10 with rick-ettsial disease.Disease was concentrated from May to Octo-ber each year.There were 14 local cases in Beijing(43.8％),with Pinggu District accounting for the highest proportion(4 cases,28.6％),16 imported cases from other provinces(50.0％),and 2 cases(6.3％)from people living abroad.The median time from disease onset to hospitalization was 8 days and the median length of hospitalization was 10 days.The mean age of patients with tick-borne diseases was 50.16±14.61(range,21-80)years.By occupation,farmers were at the greatest risk of tick-borne diseases(14 cases,43.8％).Erythema migrans(EM)was a typical skin lesion characteristic of Lyme disease,and fever was seen in all three groups,but mainly in patients with SFTS and rickettsial disease,who mainly presented with moderate fever.Decreased WBC and NEUT counts were most commonly seen in SFTS,whereas no WBC ab-normality was seen in patients with Lyme disease.Decreased EOS counts were seen in both SFTS and rickettsial disease,whereas no abnormality was seen in Lyme disease.Decreased PLT counts were typical of SFTS.Patients with rickettsial disease and SFTS showed significant liver damage with markedly elevated ALT and AST levels.Significant myocardial damage with ele-vated CK and CK-MB levels was seen in SFTS.Elevated CRP was mainly seen in rickettsial disease.Elevated PCT counts were mostly seen in rickettsial infections,followed by SFTS.The incidence of tick-borne diseases in Beijing continues to increase an-nually.Since diagnosis is often delayed,vigilant surveillance is key to improve diagnosis.Therefore,detailed epidemiological in-formation of each tick-borne disease based on clinical characteristics is needed to ensure early diagnosis and treatment.
