Research progress on therapeutic potential of mesenchymal stem cells in recurrent spontaneous abortion

VernacularTitle:间充质干细胞在复发性自然流产中治疗潜能的研究进展
Author: Qingyi WANG ¹ ; Xiaofang LIU ; Xiaoling FENG
Author Information

1. 黑龙江中医药大学,哈尔滨 150040
Keywords: Mesenchymal stem cells; Recurrent spontaneous abortion; Stem cell therapy
From: Chinese Journal of Immunology 2024;40(10):2207-2213
CountryChina
Language:Chinese
Abstract: Recurrent spontaneous abortion(RSA)is one of the most common complications in early pregnancy,affecting about 2%～5%of women of childbearing age,and its incidence is increasing year by year,which not only affects women's physical and mental health,but also causes a heavy economic burden to the society and the family.Mesenchymal stem cells(MSCs)are a class of non-hematopoietic adult multipotent stem cells derived from mesodermal mesenchymal cells of a variety of tissues.They have the characteristics of multi-directional differentiation and self-renewal,and can improve the fertility outcome of RSA patients,which has become a research hotspot in recent years.Therefore,this paper explores the roles and mechanisms of MSCs from different sources in improving pregnancy outcomes in RSA patients,and analyzes their research status and existing problems.